1. Annoyance
2. Exasperation
3. Infuriation
4. Aggravation
5. Frustration
6. Impatience
7. Exasperance
8. Peevishness
9. Pique
10. Chagrin
11. Acrimony
12. Irritability
13. Acrimoniousness
14. Peevishness
15. Petulance
16. Crossness
17. Displeasure
18. Disgruntlement
19. Discontent
20. Resentment
21. Choler
22. Annoyedness
23. Displeasedness
24. Petulancy
25. Impatience
26. Uneasiness
27. Discontentment
28. Restlessness
29. Animosity
30. Sullenness

Searching for synonyms for the word “irritation” can be a great way to expand your vocabulary. Whether you’re writing a paper, preparing a speech, or just looking for a different way to express yourself, having a list of synonyms for “irritation” can come in handy. Here are the best ideas for synonyms for “irritation”: annoyance, exasperation, infuriation, aggravation, frustration, impatience, exasperance, peevishness, pique, chagrin, acrimony, irritability, acrimoniousness, peevishness, petulance, crossness, displeasure, disgruntlement, discontent, resentment, choler, annoyedness, displeasedness, petulancy, impatience, uneasiness, discontentment, restlessness, animosity, and sullenness. With this list of synonyms for “irritation,” you should have no problem finding the perfect word to express yourself.